Shinichi Aishima Selected Research

Bile Pigments (Bilin)

8/2014	Different expression of glucose transporters in the progression of intrahepatic cholangiocarcinoma.
7/2014	Histological features of precancerous and early cancerous lesions of biliary tract carcinoma.
1/2014	Pathological diagnosis of flat epithelial lesions of the biliary tract with emphasis on biliary intraepithelial neoplasia.
11/2011	Histological and immunohistological findings in biliary intraepithelial neoplasia arising from a background of chronic biliary disease compared with liver cirrhosis of non-biliary aetiology.
4/2011	Different roles of S100P overexpression in intrahepatic cholangiocarcinoma: carcinogenesis of perihilar type and aggressive behavior of peripheral type.
4/2005	Proposal of histological criteria for intraepithelial atypical/proliferative biliary epithelial lesions of the bile duct in hepatolithiasis with respect to cholangiocarcinoma: preliminary report based on interobserver agreement.

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Shinichi Aishima Research Topics

Disease

90	Neoplasms (Cancer) 11/2022 - 05/2003
27	Hepatocellular Carcinoma (Hepatoma) 05/2020 - 11/2006
17	Cholangiocarcinoma 10/2019 - 02/2004
16	Carcinoma (Carcinomatosis) 06/2022 - 04/2005
16	Neoplasm Metastasis (Metastasis) 01/2021 - 02/2004
11	Carcinogenesis 07/2019 - 02/2009
10	Adenocarcinoma 01/2019 - 11/2011
9	Fibrosis (Cirrhosis) 01/2022 - 11/2006
9	Liver Cirrhosis (Hepatic Cirrhosis) 01/2022 - 01/2007
9	Pancreatic Neoplasms (Pancreatic Cancer) 07/2017 - 01/2010
9	Neoplasms, Cystic, Mucinous, and Serous 04/2014 - 08/2007
8	Stomach Neoplasms (Stomach Cancer) 02/2019 - 08/2013
7	Non-alcoholic Fatty Liver Disease 01/2022 - 06/2020
6	Lymphatic Metastasis 06/2022 - 02/2004
6	Breast Neoplasms (Breast Cancer) 02/2019 - 12/2010
6	Hypoxia (Hypoxemia) 01/2019 - 02/2013
4	Adenoma (Adenomas) 05/2020 - 12/2010
3	Liver Neoplasms (Liver Cancer) 10/2021 - 05/2007
3	Liver Cell Adenoma (Hepatocellular Adenoma) 02/2021 - 11/2016
3	Inflammation (Inflammations) 06/2020 - 12/2007
3	Liver Diseases (Liver Disease) 01/2018 - 09/2010
3	Neuroendocrine Tumors (Neuroendocrine Tumor) 11/2016 - 06/2012
3	Primitive Neuroectodermal Tumors (PNET) 11/2016 - 06/2012
3	Aneuploidy (Aneuploid) 01/2016 - 11/2011
3	Carcinoma in Situ 07/2014 - 12/2010
2	Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated) 01/2022 - 10/2018
2	Fatty Liver 11/2021 - 01/2021
2	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 01/2018 - 11/2011
2	Disease Progression 01/2018 - 10/2014
2	Jaundice (Icterus) 01/2018 - 10/2013
2	Gallbladder Neoplasms (Gallbladder Cancer) 01/2017 - 01/2005
2	Hepatitis C 04/2014 - 06/2013
2	Immunoglobulin G4-Related Disease 02/2014 - 09/2009

Drug/Important Bio-Agent (IBA)

14	Proteins (Proteins, Gene)FDA Link 10/2021 - 02/2004
12	Biological ProductsIBA 01/2018 - 05/2007
10	MucinsIBA 06/2022 - 05/2007
9	Biomarkers (Surrogate Marker)IBA 10/2021 - 11/2010
8	Messenger RNA (mRNA)IBA 10/2021 - 05/2003
7	Capsules (Microcapsules)IBA 01/2022 - 11/2008
7	Indicators and Reagents (Reagents)IBA 07/2019 - 02/2004
6	DNA (Deoxyribonucleic Acid)IBA 02/2021 - 11/2011
6	Fetal Proteins (Fetoprotein)IBA 04/2016 - 10/2011
6	Bile Pigments (Bilin)IBA 08/2014 - 04/2005
5	ParaffinIBA 11/2022 - 11/2011
5	Formaldehyde (Formol)FDA Link 11/2022 - 11/2011
5	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 08/2014
4	SteroidsIBA 01/2022 - 12/2007
4	Insulin (Novolin)FDA Link 01/2022 - 01/2014
4	Carrier Proteins (Binding Protein)IBA 10/2021 - 01/2015
4	Cadherins (E-Cadherin)IBA 01/2017 - 04/2011
4	MicroRNAs (MicroRNA)IBA 12/2014 - 11/2011
4	Laminin (Merosin)IBA 12/2010 - 08/2004
3	CollagenIBA 10/2020 - 01/2015
3	acarboxyprothrombin (PIVKA)IBA 05/2020 - 11/2016
3	VimentinIBA 11/2019 - 05/2013
3	alpha-Fetoproteins (alpha-Fetoprotein)IBA 11/2019 - 05/2018
3	GlypicansIBA 11/2019 - 06/2014
3	human ERBB2 proteinIBA 02/2019 - 05/2013
3	Small Interfering RNA (siRNA)IBA 01/2019 - 08/2014
3	AntibodiesIBA 01/2018 - 08/2014
3	Immunoglobulin G (IgG)IBA 01/2018 - 09/2009
3	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 01/2017 - 08/2014
3	ErbB Receptors (EGF Receptor)IBA 01/2016 - 01/2009
3	gadolinium ethoxybenzyl DTPA FDA Link 03/2015 - 12/2011
3	Progesterone Receptors (Progesterone Receptor)IBA 05/2014 - 05/2013
3	Estrogen ReceptorsIBA 05/2014 - 05/2013
3	ezrinIBA 08/2013 - 04/2011
3	fascinIBA 12/2009 - 01/2009
2	beta CateninIBA 02/2021 - 01/2009
2	CateninsIBA 02/2021 - 11/2016
2	Tumor Biomarkers (Tumor Markers)IBA 05/2020 - 05/2008
2	MART-1 AntigenIBA 11/2019 - 08/2015
2	Complementary DNA (cDNA)IBA 10/2019 - 01/2007
2	B7-H1 AntigenIBA 02/2019 - 01/2015
2	LigandsIBA 01/2019 - 07/2017
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019 - 10/2017
2	Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)IBA 08/2018 - 05/2007
2	HLA Antigens (Human Leukocyte Antigens)IBA 07/2017 - 01/2015
2	Glucose Transporter Type 1IBA 01/2017 - 11/2016
2	Insulin-Like Growth Factor II (Somatomedin A)IBA 11/2016 - 09/2013
2	Keratins (Keratin)IBA 02/2016 - 05/2007
2	Forkhead Transcription Factors (Forkhead Box Proteins)IBA 09/2015 - 04/2012
2	Hormones (Hormone)IBA 09/2015 - 04/2012
2	Fluorouracil (Carac)FDA LinkGeneric 05/2015 - 12/2013
2	Hyaluronic Acid (Hyaluronan)IBA 01/2015 - 01/2007
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2015 - 01/2007
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 10/2014 - 06/2013
2	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 09/2014 - 01/2013
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 07/2014 - 12/2013
2	Docetaxel (Taxotere)FDA Link 07/2014 - 08/2013

Therapy/Procedure

13	Hepatectomy 02/2021 - 05/2003
9	Drug Therapy (Chemotherapy) 01/2021 - 12/2010
8	Liver Transplantation 06/2015 - 11/2006
6	Pancreatectomy 07/2022 - 01/2010
6	Therapeutics 08/2021 - 12/2007
3	Radiotherapy 11/2019 - 01/2013
3	Gastrectomy 02/2019 - 09/2012
3	Adjuvant Chemotherapy 09/2015 - 04/2012
2	Thrombectomy 11/2019 - 05/2008
2	Pancreaticoduodenectomy 05/2015 - 02/2014